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Lifelong SIRT-1 Overexpression Attenuates Large Artery Stiffening With Advancing Age

System Used: Doppler Flow Velocity System In the United States, there is a progressive increase in cardiovascular diseases (CVDs) related to aging. The prevalence of

March 17, 2021

Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

  Scientists out of Vanderbilt and the University of North Carolina at Chapel Hill have established two separate organoid lines derived from active Kras-induced mouse

February 1, 2021

Development of [¹⁸F]FPy-WL12 as a PD-L1 Specific PET Imaging Peptide

System Used: SuperArgus   Programmed death ligand 1 (PD-L1) is the principal ligand of the programmed death one (PD-1) receptor and is essential in the

January 27, 2021

Pressure Arteriography or Wire Myography? How to choose for your model.

Introduction The study of vascular function is central to understanding almost every aspect of physiology, pathophysiology and pharmacology since it is the vasculature that perfuses

January 21, 2021

Transverse Aortic Constriction (TAC): Why, how and the outcome as it relates to pressure overload-induced cardiac hypertrophy and/or heart failure

Chronic congestive heart failure, more commonly referred to as heart failure (HF), is a multifactorial cardiac disease which can affect the heart both structurally and/or

January 12, 2021

Dual Energy X-Ray Absorptiometry How Does it Work?

Introduction Dual Energy X-Ray Absorptiometry (DXA/DEXA) is a technique used to assess body composition, providing measurements of bone mineral density and contentalong with lean and

December 22, 2020

The New Benchmark: How Vilber optics are revolutionizing gel and blot imaging for researchers

System Used: Newton 7.0 Whether detecting DNA, RNA, or proteins, it is challenging to find many biological publications today not using some form of gel and/or western blot documentation in their findings. While

November 23, 2020

Live cell imaging is making research easier and adding efficiency to labs under COVID-19 restrictions

  What is live cell imaging and what sets it apart?  Live cell imaging is an umbrella term that refers to a plethora of methods

July 20, 2020

Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis

System Used: M-Series MRI Tumor hypoxia and aerobic glycolysis are well-known resistance factors for anticancer therapies. Most tumour cells are subject to conditions in which

July 16, 2020

SimPET: A Preclinical PET Insert for Simultaneous PET/MR Imaging

System Used: SimPET Simultaneous Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) provides a unique non-invasive opportunity to image both the functional and structural

July 16, 2020

New Journal Article – Cell Proliferation Detected Using [18F]FLT PET/CT as an Early Marker of Abdominal Aortic Aaneurysm

System Used: SuperArgus Abdominal aortic aneurysm (AAA) is a localized dilatation of the abdominal aorta which shows limited symptomology prior to rupture. Once rupture occurs

June 26, 2020

Article: Intermittent Hypoxia (OSA) and sustained hypoxia can prompt inter-tissue circadian clock misalignment

System Used: VelO2x Circadian clocks are present in most cells of the body and act to coordinate human’s daily physiology and behavior with the environment.

June 17, 2020
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