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IL-27 Reduces Fat Accumulation in a High-Fat Diet Mouse Model

IL-27 Attenuates Fat Accumulation in a High-Fat Diet Mouse Model Leveraging NMR technology to evaluate body composition and distinguish fat mass reduction from lean tissue

July 13, 2026

Research Beyond the PIXImus: Considerations for Replacing a Legacy Small Animal DXA System

Research Beyond the PIXImus: Considerations for Replacing a Legacy Small Animal DXA System Since PIXImus is now discontinued, this article outlines considerations for replacing a

July 13, 2026

Publication Highlight: Minimally Invasive, Echocardiography-Guided Mouse Model of Degenerative Mitral Regurgitation Recapitulates Cardiac Remodeling and Arrhythmogenesis

View Paper Here Degenerative mitral valve regurgitation is a progressive disease involving the leakage of blood into the left atrium from the left ventricle during

July 10, 2026

Publication Highlight: Heterogeneous Evolution of Pancreatic Cancer Microvasculature Revealed by Longitudinal Intravital Imaging

This study uses longitudinal intravital confocal microscopy in a live PDAC mouse model to show that tumor vasculature is highly heterogeneous and dynamically unstable, with

June 26, 2026

Publication Highlight: Sleep Apnea & Idiopathic Pulmonary Fibrosis

This study investigates how intermittent hypoxia drives lung fibrosis using precise oxygen cycling with the VelO2x in vivo hypoxia chamber in bleomycin-treated mice. View Paper

May 29, 2026

The Synergistic Power of Intermittent Fasting and Threonic Acid

Publication Highlight: The Synergistic Power of Intermittent Fasting and Threonic Acid in DIO Mice This publication highlight reviews how intermittent fasting and threonic acid affected

April 27, 2026

Publication Highlight: Sirt6 Loss Promotes Disc Degeneration

Publication Highlight: Sirt6 Loss Promotes Disc Degeneration View Paper Here Authors Ramteke P, Watson B, Toci M, Tran VA, Johnston S, Tsingas M, Barve RA, Mitra R,

April 20, 2026

Publication Highlight: Mineralocorticoid receptor antagonism prevents coronary microvascular dysfunction in intermittent hypoxia independent of blood pressure

Publication Highlight: Mineralocorticoid receptor antagonism prevents Coronary microvascular dysfunction in intermittent hypoxia independent of blood pressure View Paper Here Importance Obstructive sleep apnea (OSA) is a

April 9, 2026

Publication Highlight: Mitochondrial Oxidative Stress Mediates Bradyarrhythmia in Leigh Syndrome Mitochondrial Disease Mice

Publication Highlight: Mitochondrial Oxidative Stress Mediates Bradyarrhythmia in Leigh Syndrome Mitochondrial Disease Mice View Paper Here Importance Leigh Syndrome is a severe neurodegenerative inherited disorder

April 9, 2026

Publication Highlight: T Cell-specific Non-viral DNA Delivery & In Vivo CAR-T Generation Using Targeted Lipid Nanoparticles

Publication Highlight: A Targeted Lipid Nanoparticle Platform for T Cell-Specific Non-Viral DNA Delivery & In Vivo CAR-T Generation View Paper Here Authors Jaime Fernández Bimbo,

March 20, 2026

White Paper Highlight: An Efficient and Reliable Method to Measure SpO2 in Rodents

White Paper Highlight: An Efficient and Reliable Method to Measure SpO₂ in Rodents View Paper Here Importance Peripheral oxygen saturation (SpO₂) assesses blood oxygenation and directly measures efficiency

March 19, 2026

Publication Highlight: Activation of the IKK2/NF-κB pathway in VSMCs inhibits calcified vascular stiffness in Chronic Kidney Disease

Publication Highlight: Activation of the IKK2/NF-κB pathway in VSMCs inhibits calcified vascular stiffness in Chronic Kidney Disease View Paper Here Importance Chronic kidney disease occurs

March 3, 2026
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