Rodent Surgical Monitor (RSM)

Integrated Surgical Warming and Vital Signs Monitoring

System Overview

Specifications

Webinars

Features

Features & Benefits

Model Parts & Specs

Optional Accessories

Past Webinars

System Overview

The Indus Rodent Surgical Monitor is an advanced, integrated surgical warming and vital signs monitoring solution for preclinical research in mice, rats and other small animals. The system provides detailed information, in real time, regarding subject body temperature, ECG, heart rate, pressure and respiration. The system incorporates intelligent zone heating, ultra-low noise, high-resolution ECG electronics, noninvasive electrodes, and a port for external needle electrodes for when subjects cannot be laid prone or supine.

Standard setup consists of three components:

Touchscreen Display Unit
Heated Surgical Platform
Temperature Probe

Optional components:

Pulse Oximetry Thigh Clip
Pressure Adapter Cable and Pressure Catheter
External Needle Electrodes

Temperature

Core body temperature is measured by rectal probe and regulated via the Heated Surgical Platform.

ECG

High-resolution multi-lead ECG measured by noninvasive paw or subcutaneous needle electrodes.

Heart Rate

Heart rates between 60 – 999 bpm are automatically calculated from the R peaks of the ECG signal.

Respiration

Properly titrate anesthesia based on respiration rate, measured using electrical impedance.

Pressure

Measure high fidelity arterial and ventricle pressure in mice and rats using a solid state pressure catheter.

SPO₂

Measure arterial blood oxygenation non-invasively in mice and rats using a thigh clip sensor.

Features & Benefits

Real Time Monitoring

Clearly labelled numeric panels and measurement waveforms make it easy to monitor critical parameters.

Versatile

Three sets of electrodes make it easy to work with small mice, large rats and many small animals in between.

Ultra-Low Signal Noise

Enhanced design minimizes interference for clean, accurate physiological data you can trust.

Easy Documentation

A single image can capture animal ID, vital signs, study ID, researcher, date, time and all filter settings.

Standalone Data Collection

Capture data, make comments and view recordings on the tablet to quickly take measurements and verify experiment details.

Electrically Isolated Bio-Amplifiers

Prevents cross-talk and artifact distortion, enabling clear, high-fidelity signal acquisition.

Seamless Data Export

effortlessly integrates with third-party software for advanced analytics and streamlined workflows.

Customizable Presets

Define optimal study conditions and ensure consistency between subjects and collaborating labs.

Flexible

Expansion modules allow you to easily add functionality later as your lab and study’s needs change.

Consistent Thermal Regulation

Built-in heating ensures temperature stability for your experimental animals, boosting reproducibility.

Electrically Isolated Bio-Amplifiers

Prevents cross-talk and artifact distortion, enabling clear, high-fidelity signal acquisition.

Model Parts & Specifications

Touchscreen Display Unit

Configurable, clear waveforms and numeric panels provide information to monitor subject physiological status. Recording, playback and export functions are included to make data collection easy.


Content	High Resolution Color Display with Capacitive Touch
Size & Resolution	12.7 inches; 1840 x 2944 pixels
Storage Capacity	128 GB of Data Storage
Power Supply	Universal Adapter (100 – 240 VAC)
Connection to the Heated Surgical Platform	Wireless or optional USB-C

Physiologic Measurements

Range	Measurement
Heart Rate (Lead I, II, II)	30-960 BPM
Respiration Rate	15-300 BrPM
Core Temperature	25 – 50°C
Pad Temperature	25.0 – 43.5°C
R-R Interval (Lead I, II, III)	60 – 1000 ms
SpO2 *	80 – 100%
Pressure **	-50 – 300 mmHg

Waveform Display Options
ECG Lead I, II, III
ECG Lead aVL, aVR, aVF
Respiration
Respiration (from ECG)
Pulse Plethysmogram *
Pressure **

Heated Surgical Platform

Configurable, clear waveforms and numeric panels provide information to monitor subject physiological status. Recording, playback and export functions are included to make data collection easy.


Dimensions	7.6 x 11.6 x 0.75 inches
Weight	1.94 pounds
Heater Type	Responsive with Multiple Zone Control
Heater Uniformity	< 0.5°C Across Active Area
Startup Time	< 2 minutes from room temperature
Heater Set Temperature	Adjustable, 25.0 – 43.5°C by 0.1°C
Power Supply	Universal Adapter (100-240 VAC)
Noninvasive Electrodes	Two sets of limb ECG contact electrodes; inner set for mouse, outer for rats or subjects of similar size
Optional External Electrodes	3.5mm 4-pole audio jack to four 13mm stainless steel needle electrodes

Temperature Probe

Each Rodent Surgical Monitor⁺is delivered with a single rectal temperature probe. Customers may select between probes optimized for neonatal mice, adult mice, or rats.

The temperature probe sensor is a Copper-Constantan Thermocouple, located at the tip of the probe. Probe temperature and accuracy is +/-0.1°C.

RSM oX Model

Additional Oxygen Saturation Capabilities

Patent-Pending Technology – Integrated PulseOx sensors built directly onto the platform via the embedded stainless-steel electrode
Reduce Noise and Variability – No longer worry about poor sensor placement, fur interfering with measurement, noise from respiration or cable movement
Optimal and Stable Measurement – Reproducibly measure from a consistent site.

Optional Accessories

Pressure Catheter Option

Pulse Oximetery Option

4 or 8 Channel Analog Output Cable

Pressure Catheter Option

The Pressure Catheter Option includes a software and firmware update, along with a catheter connection cable. When connected to an Indus pressure catheter, measurements of arterial and ventricular pressures can be performed. This adds another real-time continuous data stream to the Rodent Surgical Monitor+. The Indus high fidelity rodent pressure catheters are specifically designed for use with mice and rats. These catheters have solid state sensors mounted at the tip that measure pressures with a high degree of precision. They are ideal for arterial, venous, or ventricular pressures due to the solid state sensor’s ability to accurately respond to minute and rapid changes in pressure.

Pressure Catheter Specifications


Available Sizes	1.2F and 1.6F
Sensor Type	Solid state sensor, mounted at the tip of the catheter; pressure membrane recessed for protection
Catheter Material	Polymide tubing, providing balance of flexibility and rigidity
Pressure Resolution	10uV/mmHg; higher than the industry standard

Pressure Amplifier Specifications


Input Pressure Range	-50 – 300 mmHg
High Pass Filter Settings	None
Low Pass Filter Settings	Can be set to Off, 30Hz, 100Hz, 200Hz, 500Hz, or 1000Hz
Notch Filter Settings	Can be set to Off, 50Hz, or 60Hz
Calibration	Allows zero calibration and a high-point calibration

Pulse Oximetery Option

Pulse Oximeter Option

The Pulse Oximeter Option includes a software and firmware update, along with a sensor clip. This option allows you to noninvasively measure arterial blood oxygenation. This adds another real-time continuous data stream to the Rodent Surgical Monitor⁺, providing valuable information about depth of anesthesia and ventilation efficacy. Pulse oximetry has been mandated in hospital care for more than a decade: the preclinical research community has taken note of this and current NIH guidelines repeatedly suggest monitoring pulse oximetry during surgery and postoperative care to ensure correct anesthesia delivery and ventilation.

Cable Specifications


Pulse Rate Range	200-999 BPM
Pulse Rate Resolution	1 BPM
Sp02 Range	80% – 100%
Sp02 Resolution	1%
Connector	Built-In Connector
Available Sensors	Thigh Clip (Mouse & Rat)

4 or 8 Channel Analog Output Cable

The 4 or 8 Channel Analog Output Cable provides the capability to acquire raw data from the Rodent Surgical Monitor+, in real time, with virtually any data acquisition system. A total of four or eight output channels are included, each configurable for optimal data output. In addition, the cable can be used as an R-trigger for ultrasound imaging systems, as a TTL trigger for high-speed dual camera image capture systems and to supply data to many different brands of data acquisition systems. Each channel can be individually configured with its own filtering options.

Available Signal Outputs


ECG Lead I, II, III	ECG Lead II Trigger
Respiration Waveform	Core Temperature
Pad Temperature	Pulse Plethysmography (IR)
Pulse Plethysmography (R)	Pressure

Analog Output Specifications


BNC Outputs	4 or 8 Channels
Sample Rate	4 kHz
DAC Resolution	14-bit
Output Impedance	75 ohms typical
Output Voltage	± 5V
Maximum Output Current	30mA short circuit current
Slew Rates	1.8V per microsecond
Settling Time	5µs typical
Linearity Error	± 1 LSB
High Pass Filtering	Can be set to Off, 0.2Hz, 0.5Hz, 1Hz, 2Hz, 5Hz, or 10Hz
Low Pass Filtering	Can be set to Off, 1Hz, 2Hz, 5Hz, 10Hz, 20Hz, 30Hz, 100Hz, 200Hz, 500Hz, or 1000Hz. There is also a 2000Hz hardware filter setting
Notch Filtering	This filter suppresses cyclic 50Hz or 60Hz AC power line noise that can interfere with the instrumentation.