(Dec 11th, 2024) The Paradigm Shift from Normoxia to Physoxia: Enhancing Experimental Precision for Better Translational Outcomes
The Paradigm Shift from Normoxia to Physoxia: Enhancing Experimental Precision for Better Translational
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar, we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allow for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Abi Karunendiran, PhD, is an application specialist with extensive experience in microscopy. She holds an MSc and an PhD from the University of Toronto in Cell and Systems Biology where she worked in an interdisciplinary environment, merging the fields of multi-photon microscopy and cell biology. Supplemented by a two-year postdoctoral fellowship at Harvard Medical School focused on intravital microscopy, she brings a comprehensive academic background to her current role. As an application specialist, she is dedicated to connecting with researchers to highlight the advancing field of intravital microscopy how it can help support their research applications.
The Paradigm Shift from Normoxia to Physoxia: Enhancing Experimental Precision for Better Translational
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