Science Blog

8 Reasons to Choose the Newton 7.0 for In Vivo Imaging

The Newton 7.0 sets a new benchmark in preclinical optical imaging. Designed for reliability and versatility, it enables researchers to visualize biological processes in real time with uncompromising image quality and ease of use. 

Here are 
eight reasons researchers choose the Newton 7.0 for
 in vivo imaging excellence:  

1. A Wider Lens Aperture 

The Newton 7.0 uses the widest available lens aperture at f/0.70, allowing more light collection, even from low-signal samples. This allows for faster acquisition times and higher sensitivity – ideal for in vivo studies 

2. High Resolution CCD Camera

All Newton 7.0 systems feature a scientificgrade CCD camera for signal detection. The VIS camera is deeply cooled to –90°(absolute) to reducdark noise and enhance image quality. With a resolution of 4.6 MP, images are produced with the best signal-to-noise ratio.  

3. Powerful Illumination System

Newton 7.0 achieves imaging versatility with 8 to 12 excitation sources (model-dependent), allowing users to track and visualize a variety of fluorescent reporters. The class II LEDs encompass a very narrow-band illumination, increasing sensitivity and reducing crossstimulation, without the need for excitation filters.  

4. Fully Automatic Darkroom

The motorized camera and mousepad allow users to navigate the FOV with easeAcquire images from up to 10 mice simultaneously using the largest FOV (20 x 20 cm), facilitating the highest throughputs.  

5. 3D Optical Tomography Capabilities 

Optical tomography provides in-depth quantitative and localized analysis for signal distribution within an animal using body surface measurements and two 3D camerasThe Newton 7.0 reconstructs bioluminescent signals into volume, which is overlaid by its 3D model for a better understanding of anatomical and deep tissue structures.  

6. Multi-spectral Capabilities 

With multi-spectral imaging (i.e., multiplexing), the Newton 7.0 enables precise separation of fluorescent and bioluminescent signals in a single acquisition session. Researchers can perform co-localization studies such that various signals can be visualized simultaneously.  

7. License-Free Software 

The Newton 7.0 comes equipped with license-free acquisition and analysis software, designed to be intuitive and user-friendly. The software allows every user to analyze, process and share data without restrictions or extra costs 

8. Fast, Intuitive Workflow 

From acquisition to analysis, the user-friendly software interface streamlines every stepThe Newton 7.0 offers premade protocols, smart autofocus, and real-time previews to help users save time and reduce variability between experiments. Flexible imaging modes between bioluminescence and fluorescence support a wide range of probes and dyes