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Preclinical CRO Services:

Study execution for biotech, pharmaceutical, and academic research teams.

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Multimodal imaging including MRI, PET/CT, optical, ultrasound, and DXA.

Scientific Imaging Expertise

Work with a team experienced in study planning, image acquisition, and quantitative analysis. We support preclinical research in oncology, neuroscience, metabolism, cardiovascular, musculoskeletal, and regenerative medicine. Our focus is reliable data, clean execution, and clear deliverables.

Typical Deliverables
  • Study plan and imaging workflow
  • Processed datasets and quantitative outputs
  • Clear reporting with methods and results
Tell us about your study and we’ll recommend the best imaging approach.
Preclinical imaging modalities collage
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Services Provided

State-of-the-art in vivo imaging solutions, offering a comprehensive range of modalities:

  • Magnetic Resonance Imaging (MRI) – High-resolution anatomical and functional imaging for brain, tumor, and organ studies.
  • in vivo Optical Imaging – Monitoring cellular and molecular events with bioluminescence or fluorescence imaging.
  • Positron Emission Tomography (PET/CT) – Quantitative, high-sensitivity imaging for metabolic and tracer-based studies.
  • Single Photon Emission Computed Tomography (SPECT/CT) – High-resolution functional and anatomical data to support drug development.
  • DEXA (Dual-Energy X-ray Absorptiometry) – Bone mineral density (BMD), body composition, and lean and fat mass distribution in small animals.
  • Short-Wave Infrared (SWIR) Imaging – Deep tissue penetration and enhanced contrast for real-time drug biodistribution.
  • Wide-Field Calcium Imaging – Functional connectivity studies and imaging cortex-wide neuronal signaling with genetically encoded calcium indicators.
  • Confocal Microscopy Imaging – High-resolution optical sectioning for detailed visualization of cells and tissues.
  • Super-Resolution Imaging – Nanometer-scale imaging that surpasses the diffraction limit for ultra-fine structural detail.
  • Live Cell Imaging – Time-lapse microscopy capturing dynamic cellular processes in real time under physiological conditions.
  • Intravital and Deep Tissue Imaging – Imaging within living organisms to visualize cellular interactions in intact, deep biological tissues.

Our spatial biology pipelines are fully integrated into H&E and IHC detections and include:

  • Full-Service Spatial Transcriptomics using the Xenium In Situ instrument for single-cell gene expression mapping within intact tissue.
  • Comprehensive Tissue Microarray (TMA) Construction services enabling efficient and standardized analysis of large tissue cohorts.
  • Fresh and FFPE Tissue Single-Cell RNA-Seq (scRNA-Seq) offering high-quality single-cell RNA sequencing with specialized workflows optimized for FFPE tissue interpretation.

Analytical services to support drug discovery, contrast agent development, and biomolecular research. Using advanced NMR, HPLC, and LC-MS technologies, we provide precise characterization, quantification, and quality control of small molecules, contrast agents, and biologics.

  • LC-MS and MS – Drug quantification, purity analysis, metabolic profiling, DMPK, and structural elucidation.
  • NMR Spectroscopy (¹H, ¹³C, 2D NMR, and more) – Structural determination, impurity profiling, confirming metabolic pathways, and confirmation of compound identity.
  • HPLC Services – Small-molecule characterization, impurity analysis, stability studies, and method optimization.
  • Tissue Processing and Embedding
  • Sectioning
  • Special Stains > 20
  • General Staining
  • RNAscope
  • Imaging
  • Multiplex IHC and IF
  • Opal
  • Scanning
  • Study Scoping and Hypothesis Refinement: Clarifying scientific questions and defining endpoints.
  • Model Selection and Cohort Definition: Recommending appropriate in vitro and in vivo models.
  • Dosing Strategy and Sampling Schedule: Designing routes, dose levels, and time points.
  • Imaging and Analytical Endpoint Integration: Coordinating imaging with analytical readouts.
  • Randomization, Blinding, and Bias Control: Implementing robust study controls.
  • Power and Statistical Planning: Ensuring adequate study power.
  • Data Structure and Analysis-Ready Outputs: Streamlining downstream analysis.
  • Documentation, SOPs, and Reporting Framework: Preparing protocol and reporting templates.