WMIC 2023 Oral Presentation: Multiplexed PET for Dual Radiotracer PET Imaging

Don’t miss out on Dr. Edwin C. Pratt’s Oral Presentation at WMIC 2023! 

Discover groundbreaking research oral presentation scheduled for Friday, September 08, 2023, starting at 1:00 PM to 2:30 PM.

Immerse yourself in a world of innovation as we unveil the remarkable study titled:

🔬 Multiplexed PET for Dual Radiotracer PET Imaging 🦠

PET imaging is a powerful noninvasive imaging modality based on the detection of the annihilation gamma rays from the positrons emitted by an administered radiotracer. Reconstruction methods for PET focus on this methodology, excluding coincidences from isotopes that emit gamma rays in addition to the positron emission. Here, multiplexed PET leverages prompt gamma emissions from positron-gamma emitters to enable truly simultaneous dual-isotope PET imaging without . By using this new reconstruction method, existing clinical and preclinical PET scanners capable of recording events beyond standard coincidences can now be used for dual PET tracer studies. Isotopes that enable multiplexing include 44Sc, 52Mn, 72As, 86Y, and 124I. We show examples of dual small molecule imaging with 18FDG and 124I-trametininb, nanoparticle tracking in lung as well as melanoma models, as well as CAR-T targeting for PSMA+ tumors. We also show new phantoms for mPET and reconstruction improvements to the mPET method using deep learning to reduce the noise of the images and improve the accuracy of the isotope separation.

*Pratt, E.C., Lopez-Montes, A., Volpe, A. et al. Simultaneous quantitative imaging of two PET radiotracers via the detection of positron–electron annihilation and prompt gamma emissions. Nat. Biomed. Eng (2023). https://doi.org/10.1038/s41551-023-01060-y

Join us at WMIC 2023 as we illuminate the path to a safer and healthier world. See you at the session!

🔗 Session Details:
Title: Multiplexed PET for Dual Radiotracer PET Imaging
: Friday, September 08, 2023
Time: 1:00 PM – 2:30 PM
Location: Prague Congress Centre

WMIC Program: WMIC Program Link

Publication: Publication Link

Dr. Edwin Pratt will also be having a webinar about his research!

Title: Seeing Double: Preclinical Multiplexed PET for Dual Isotope Imaging
Date: September 13th, 2023
Time: 11:00 AM (EST)

Special thanks to Dr. Edwin Chuck Pratt, Dr. Joaquin L. Herraiz & every researcher that was part of this project:

Dr. Alejandro Lopez-Montes
Dr. Alessia Volpe
Dr. Michael J. Crowley
Dr. Lukas M. Carter
Dr. Vivek Mittal
Dr. Nagavarakishore Pillarsetty
Dr. Vladimir Ponomarev
Dr. Jose M. Udias
Dr. Jan Grimm

Without the collaboration of each member, this research would not have been possible.

Book a Meeting with Scintica

Read more about Science!