Seeing Double: Multiplexed PET for Dual Isotope Imaging at SFN 2023

Join us on November 15, 2023, at 11:30 am at SFN 2023. 

Dr. Edwin Pratt will delve into the innovative concept of multiplexed PET,  making it possible to perform simultaneous imaging with two different isotopes providing more in-depth information with a single scan!

Overview:

Explore the realm of PET imaging and the new concept of multiplexed PET. This scientific advancement makes it possible to perform simultaneous imaging with 2 different isotopes providing more in-depth information with a single scan. 

Multiplexed PET uses prompt gamma emissions from positron-gamma emitters to enable truly simultaneous dual-isotope PET imaging. This reconstruction method allows PET scanners to record events beyond standard coincidences and can be used for dual PET tracer studies.

  • Multiplexed PET is a new reconstruction method to identify and separate positron from positron-prompt gamma emissions without new hardware from list mode PET scanners or energy discrimination of events.
  • Multiplexed PET is a quantitative method that is agnostic to the type of radiotracer used (IE no compartment modeling). Only a simple uniformity and sensitivity phantom is required.
  • Multiplexed PET enables faster throughput for screening radiotracers, or conversely two tracer information of a tissue of interest, like imaging the tumor microenvironment for two immune populations.
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