Gel Documentation Systems

DNA and RNA gels and fluorescence stain imaging

Applications

Features

System Overview

 VILBER is a leading life science company developing and manufacturing fluorescence, chemiluminescence and bioluminescence imaging systems for applications ranging from Gel documentation to small animal preclinical research. Founded in 1954, Vilber is a leader in the molecular imaging sector and develop equipment with high standard quality, equipping more than 20,000 laboratories worldwide. An estimated 60,000 researchers use their products every day in over 100 countries.

VILBER Gel Documentation systems are the ideal imaging systems for gel visualization and documentation in any lab or core facility. The Super-Bright UV illumination, the emission filter with large spectrum technology and the camera with high resolution enhances the image quality, especially for analysis of agarose gels (DNA and RNA) and Polyacrylamide Gels (Proteins). The robust and compact darkroom is made entirely of stainless steel and aluminum.

 

Fluorescence is the main method used to detect samples of DNA and RNA in agarose gels. If you work with Molecular Biology techniques as PCR reaction, excision of bands from gels for purification, analysis of fragments after restriction reactions with enzymes, genotyping, Molecular Cloning, electrophoresis, protein expression and purification, you need to check out the Gel-Doc Systems from Vilber. The Gel-Doc systems are very useful to obtain images with high quality to publications. It offers the best sensitivity and speed, and reaches the lowest limits of detection for your DNA, RNA and protein applications.

 

VILBER offers a wide array of technologies to fit any application needed while offering unsurpassed sensitivity, speed, and the ability to reach the lowest limits of detection for DNA, RNA and protein applications. From basic systems that “get the job done” to the highest specification gel documentation stations on the market, the VILBER line has every researcher and technically challenging application covered.

Features & Benefits

Gel documentation systems are widely used in molecular biology labs for the imaging and documenting of nucleic acid and protein polyacrylamide or agarose gels typically stained with ethidium bromide or fluorophores such as SYBR green.

The E-Box is a highly sensitive optical imaging system dedicated to gel documentation with the ability to be upgraded to other applications as researchers needs shift. It combines the best optics with simple software for optimum scientific images and results.

Transilluminator with exclusive “Super-Bright” Technology 

It eliminates the interference and background caused by blue light.Images with high quality, resolution and sharper bands.

590nm emission filter with large spectrum range (540 to 640 nm)

It allows to detect a huge range of stains/dyes using only 1 filter. No need to use/buy more than 1 filter = Economy. Dyes as Ethidium Bromide, Sybr-Safe, Sybr-Green, Gel-Red, Gel-Green, Sybr-Gold, GFP, Pro-Q Emerald, Sypro Ruby, FITC, DAPI can be detected.

PadBox Concept (It depends of the model)

Interchangeable Application Pads for excitation with UV, Blue and White lights.
The transilluminator version is equipped with a slide-out UV table for easier sample
handling. It is very convenient to position and to cut the gel outside the cabinet and then to slide it inside for acquisition.

High Resolution Camera

Excellent resolution and gray levels to detect the finest details.

Hardware

Smart Darkroom technology: Software control of the lighting, white light led panels with automatic intensity adjustment. Optional slide-out PadBox with automatic recognition of the Application Pad inserted (It depends of the model). Robust stainless and aluminum darkroom. Wide access door with UV safety shut-off for protection of the user.

Easy to use

One-Click-to-the-Image: Auto-exposure, Auto-focus and Auto-lighting.

Technologies and Innovation

Apps Studio (an innovative library of applications which contains more than 40 different protocols pre-saved to better adjust to the image), 3D Dynamics Scan (view of the bands in 3D).

License-Free Acquisition and Analysis Software

Free software for image acquisition with full GLP compliance. Molecular weight calculation, band quantification, colony counting, distance calculation, text annotation and image enhancement included.

Models & Specifications

Applications

The PadBox is a slide-out container which can welcome several light sources for excitation in the UV, the blue, the green and the red spectrums. As gel documentation moves from single UV excitation source to a wide variety of lighting options, the PadBox concept meet the need for accommodating into one device several interchangeable light sources..

The Pads we offer:

Super-Bright UV Pad:

To analysis, visualization and documentation imaging of DNA and RNA samples in agarose gels. As well as proteins in colorimetric stained gels.

Fluorescence stain imaging in Agarose Gels:
✓ Ethidium Bromide
✓ Sybr-Safe
✓ Sybr-Green
✓ Gel-Red
✓ Gel-Green
✓ Sybr-Gold
✓ GFP
✓ Pro-Q Emerald
✓ Sypro Ruby
✓ FITC
✓ DAPI

White Pad or white light conversion screen:

Colorimetric Stained Protein Gels: Coomassie blue, Silver stain, Ponceau S Red, Copper stain:
Coomassie
ls blue
Silver stain
Autorads
Ponceau S red
Copper stain

Sky-Pad or blue light conversion screen:

470 nm light for DNA/RNA detection (avoid nicking and degradation)

Publications & Articles

Read more about how our instruments and systems have leveraged the research work of many scientists around the globe.