DELab µCT-100

In vivo animal and ex vivo 3D sample micro computed tomography (µCT) for preclinical research

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System Overview

The DELab micro computed tomography-100 (µCT-100) is designed specifically for in vivo imaging of small laboratory animals and ex vivo isolated samples. Research applications of the system range from musculoskeletal and metabolic disease, oncology, drug/therapeutic development, cardiology, anatomy, food science, and geology.

The DELab µCT-100 is a fully self-shielded system designed for analysis of ex vivo samples and in vivo small laboratory animals such as mice and rats or similar sized animals up to 350g. The fast scan mode can reduce scan times down to 2 seconds which can be ideal for screening. While the ultra-high-resolution mode optimizes the scan time for resolution down to 1.5µm with image reconstruction. Various modes allow the user to choose their ideal scan time or resolution. The user-friendly application modes are optimized for bone, lung, soft tissue, and metal material (i.e. implants). The x-ray dosage is conveniently tracked for animal monitoring and can range from 0.57 -180 mGy/s. Further animal welfare features of the system include LED surveillance camera, physiological monitoring, airflow heating, and anesthesia gas system.

The DELab µCT-100 can measure the following physical parameters:
– Total volume (TV) (mm3)
– Bone volume (BV)
– Bone mineral density (BMD)
– Ratio of bone and tissue volume (BV/TV)
– Average cortical bone thickness (µm)
– Trabecular bone thickness (µm)
– Number of trabecular bones (Tb. N)
– Ventilation – Inspiration and Expiration – volume (mm3)
– Ratio of body fat to body volume (BF/TV)

Features & Benefits

Fast scan mode allows a 2-second scan time

Fast scan time for high-throughput imaging studies.

Multiple animal beds for different species

The DELab µCT-100 has rat (80mm x 200mm), mouse (40mm x 200mm), and ex vivo sample (10mm x 200mm) bed options for a range of study designs and applications.

Adjustable high-resolution image acquisition down to 1.5µm with image reconstruction

The DELab µCT-100 can acquire images within a range of resolutions from 1.5µm – 44.9µm.

Comprehensive animal welfare features

The DELab µCT-100 has independent controllable heated airflow and anesthesia gas systems for maintaining a stable animal status. Additionally, the DELab µCT-100 has an embedded LED camera for real-time animal monitoring. ECG and respiratory gating are displayed on the interface.

Automatic animal bed and FOV recognition

With One Touch auto-setting, the DELab µCT-100 software recognizes the animal bed size in use and automatically adjusts the field of view (FOV). 

Built in syringe pump

The DELab µCT-100 can automatically inject contrast agents during scanning for enhanced soft tissue imaging and enables further applications for the researcher.

Fully self-shielded design

A fully self-shielded design makes the DELab µCT-100 ideal for use in shared spaces and does not require additional safety precautions.

Specifications

Specification Rat Mode (all beds) Mouse Mode (all beds) Ex Vivo/In Vivo Mode (mouse/ex vivo bed) Ultra-High Resolution (ex vivo bed)
Scan Method
Gantry dual energy cone beam CT
Gantry dual energy cone beam CT
Gantry dual energy cone beam CT
Gantry dual energy cone beam CT
Animal Size
2-350g
2-350g
2-35g
2-20g
Scan Time
2s (fast scan mode) 20s
2s (fast scan mode) 36s
111s
272s
Field of View (maximum W x L)
80mm x 180mm
40mm x 135mm
23mm x 90mm
10mm x 54mm
Image Resolution (with reconstruction)
44.9 μm (22.45-180 μm)
22.5 μm (11.25-90 μm)
15 μm (7.5-60 μm)
9 μm (1.5-36 μm)
Dose Rate (mGy/s in air)
0.57~127 mGy/s
0.7~178 mGy/s
0.8~162 mGy/s
0.8~170 mGy/s
Operating System
Windows 11
Windows 11
Windows 11
Windows 11
Dimensions (WxDxH)
880 x 1500 x 1500mm (950kg)
880 x 1500 x 1500mm (950kg)
880 x 1500 x 1500mm (950kg)
880 x 1500 x 1500mm (950kg)
Power
100-240V~/50-60Hz/5.85 A
100-240V~/50-60Hz/5.85 A
100-240V~/50-60Hz/5.85 A
100-240V~/50-60Hz/5.85 A
Operating Temp
10-30℃
10-30℃
10-30℃
10-30℃

Resources

Publications & Articles

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