(November 14, 2024) NIR-II Fluorescence imaging: Why, When and How
(November 14, 2024) NIR-II Fluorescence imaging: Why, When and How Short-Wave Infrared (SWIR)
Ultrasound color Doppler imaging has been routinely used for the diagnosis of cardiovascular diseases, enabling real-time flow visualization through the Doppler effect. Yet, its inability to provide true flow velocity vectors due to its one-dimensional detection limits its efficacy. To overcome this limitation, various VFI schemes, including multi-angle beams, speckle tracking, and transverse oscillation, have been explored, with some already available commercially. However, many of these methods still rely on autocorrelation, which poses inherent issues such as underestimation, aliasing, and the need for large ensemble sizes. Conversely, speckle-tracking-based VFI enables lateral velocity estimation but suffers from significantly lower accuracy compared to axial velocity measurements.
To address these challenges, we will present a speckle-tracking-based VFI approach utilizing multi-angle ultrafast plane wave imaging. Our approach involves estimating axial velocity components projected onto individual steered plane waves, which are then combined to derive the velocity vector. Additionally, we will introduce a VFI visualization technique with high spatial and temporal resolutions capable of tracking flow particle trajectories.
Simulation and flow phantom experiments demonstrate that the proposed VFI method outperforms both speckle-tracking-based VFI and autocorrelation VFI counterparts by at least a factor of three. Furthermore, in vivo measurements on carotid arteries using the Prodigy ultrasound scanner demonstrate the effectiveness of our approach compared to existing methods, providing a more robust imaging tool for hemodynamic studies.
Learning objectives for the attendees:
Geng-Shi Jeng is an accomplished engineer and researcher with a B.S. in Electronics Engineering from National Chiao Tung University (1996), and M.S. and Ph.D. degrees in Electrical Engineering from National Taiwan University (1998, 2005). He began his career at the Industrial Technology Research Institute (ITRI) before serving as Director at Coretronic Corporation. Joining S-Sharp Corporation in 2011 as CTO and CEO, he spearheaded the development of cutting-edge ultrasound technologies, including high-frequency preclinical imaging systems, research-oriented array platforms, portable ultrasound devices, and ultrasound reflection tomography. He furthered his expertise as a Visiting Scientist in the Department of BioEngineering at the University of Washington, Seattle (2017-2019). Currently an Associate Professor at National Yang Ming Chiao Tung University, his research spans real-time ultrasound systems, beamforming, Doppler flow imaging, cardiac elastography, contactless ultrasound biometric detection, underwater imaging, and photoacoustic imaging.
(November 14, 2024) NIR-II Fluorescence imaging: Why, When and How Short-Wave Infrared (SWIR)
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