Science Blog

The Role of X-ray Absorptiometry in Preclinical Research

Preclinical research is being revolutionized by advanced imaging technologies. As a critical phase in the development of medical therapies, it can help us to enhance our understanding of diseases. Among these technologies, the Dual Energy X-ray Absorptiometry (DXA) stands out, especially the iNSiGHT DXA system, which can be tailored for vivo applications within the field of medicine. 

Technology and Applications

DXA, with its dual-energy x-ray capability, offers precise body composition measurements. These are crucial for studying metabolic disorders and musculoskeletal pathologies. The iNSiGHT DXA system’s comprehensive solution caters to a wide range of applications, from osteoporosis and arthritis to diabetes and obesity. It also proves vital in understanding bone regeneration and muscle wasting diseases, broadening its scope in preclinical research.

System Features

The iNSiGHT system simplifies data acquisition with minimal preparation, emphasizing animal safety with an integrated anesthesia system. Its large scan area accommodates various animal models, from small rodents to non-human primates, enhancing its research applicability. The system’s rapid scan time, a mere 25 seconds, is unmatched, enabling high-throughput imaging. In a single scan, it generates an x-ray attenuated image, a bone mineral density map, and a color map, providing a comprehensive analysis of bone mineral content, density, area, and body composition.

Safety and Efficiency

Prioritizing research subject safety, the iNSiGHT system utilizes low-dose radiation (0.66 mGy) to prevent any adverse effects on the subjects during longitudinal studies. This feature is paramount in preserving the integrity of the research and welfare of the animal subjects.

Technical Specifications

Operating on Windows 10 and accommodating animals up to 5kg, the iNSiGHT system’s technical specifications are designed to meet your diverse requirements. It has an adjustable field of view and resolution and can be customized to suit your specific research needs. Alongside this, by utilizing a cone-beam scan method and varying pixel sizes, the system offers flexibility in image resolution and detail. 

Additional Features

Enhancing its utility, the iNSiGHT system incorporates anesthesia control, a high-resolution digital radiography mode, and offline analysis software. These features contribute to its status as a versatile and efficient tool in preclinical research settings.

The iNSiGHT DXA system is here to help with your medical research

The iNSiGHT DXA system represents a significant advancement in preclinical research. Thanks to the accuracy and detail provided by its imaging capabilities, we understand more about various diseases and conditions, including complex metabolic and musculoskeletal disorders. As a result, this can help with the development of future medical therapies.

For more information about the iNSiGHT DXA system, contact Scintica at any time.