PET/CT
The SuperArgus PET/CT incorporates state-of-the-art detectors and electronics as the latest evolution of the Argus PET/CT family of scanners.
SuperArgus
The SuperArgus line of instruments include PET only, CT only, or combined PET/CT systems, with a wide range of available bore sizes allowing for a variety of animal models to be imaged. These state-of-the-art systems incorporate a phoswich PET detector, which provides true depth of interaction (DoI) information resulting in enhanced resolution. The systems are self-shielded, allowing them to be installed in any existing laboratory or animal facility space, without the need for additional infrastructure.
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Publications SuperArgus PET/CT
Illumination Effect
Effect of Illumination level [18F]FDG-PETbrain uptake in free moving mice.
Analysis of Glucose Metabolism
Analysis of glucose metabolism by 18F-FDG-PET imaging and glucose transporter expression in a mouse model of intracerebral hemorrahge
Synthesis & evaluation
Discovery, synthesis and evaluation of novel reversiblemonoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold
Binocular 3D otolith-ocular reflexes
Binocular 3D otolith-ocular reflexes: responses of chinchillas to prosthetic electrical stimulation targeting the utricle and saccule
Radiosynthesis
Revisiting the Radiosynthesis of [18F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer’s Disease
Evaluation of 124 I-JS001
Evaluation of 124 I-JS001 for hPD1 immuno-PET imaging using sarcoma cell homografts in humanized mice
- Chaney, A. M. et al. Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: A collaborative multi-modal study. Theranostics 11, 6644–6667 (2021). DOI: 10.7150/thno.56059
- España, S. et al. In vivo production of fluorine-18 in a chicken egg tumor model of breast cancer for proton therapy range verification. Scientific Reports 12, (2022). DOI: https://doi.org/10.1038/s41598-022-11037-7
- Kumar, D. et al. Peptide-based PET quantifies target engagement of PD-L1 therapeutics. Journal of Clinical Investigation 129, 616–630 (2019). DOI: 10.1172/JCI122216
- Yeh, S. H. H. et al. Automated Synthesis and Initial Evaluation of (4′-Amino-5′,8′-difluoro-1′ H-spiro[piperidine-4,2′-quinazolin]-1-yl)(4-[18F]fluorophenyl)methanone for PET/MR Imaging of Inducible Nitric Oxide Synthase. Molecular Imaging 2021, (2021). DOI: 10.1155/2021/9996125
- Efthimiou, N. et al. Influence of Multiple Animal Scanning on Image Quality for the Sedecal SuperArgus2R Preclinical PET Scanner. Frontiers in Physics 8, (2021).DOI: https://doi.org/10.3389/fphy.2020.531662
