The Indus Small Animal Telemetry System and associated wireless implants offer a simplified and cost-effective approach to studying physiology in conscious, unrestrained small animals. Scientists are able to monitor ECG, heart rate, core body temperature and activity in multiple, socially housed animals simultaneously.

 

The system consists of three core components:

• Wireless Implant
• Wireless Charger Pad with Analog Outputs
• Online Configurator

 

The Indus Telemetry systems combines digital telemetry with wireless power technology.

Advantages of Telemetry – Conscious, unrestrained, long-term

• Conscious. Following surgical recovery, data is recorded from conscious animals capable of moving and engaging in normal behaviors. The ability to conduct conscious recordings also eliminates the possible influence of anesthesia on physiological signals.
• Unrestrained. Animal handling and restraint can induce a stress response. Telemetry eliminates this unnecessary animal stress.
• Long-term. Telemetry data recording allows researchers to record, analyze and observe the development of pathology over days, weeks or months without missing a specific data timepoint. Further, within-animal design, can enhance statistical power and reduce the number of animals required

The Three Rs of Animal Research

The 3Rs (Replacement, Reduction, and Refinement), introduced in 1959 by William Russell and Rex Burch and discussed more frequently in the past 15 years, serve as guidelines when designing experiments involving animals. The Doppler Flow Velocity System embraces these concepts in its design and everyday use.

• By collecting data serially, researchers are able to both gather more data and gain extra control over variability – Reducing the number of animals potentially required used per study.
• Refining catheter-based or other invasive measurements by using noninvasive handheld probes decreases unnecessary pain.
• Further, the small diameter of these probes allow measurements that would be difficult or impossible with systems with larger footprints.

Learn more about the 3Rs of Animal Research:

• The Principles of Humane Experimental Technique [W.M.S. Russell and R.L. Burch]
• Replacement, Reduction and Refinement [Paul Flecknell]
• UK’s National Centre for the Replacement Refinement & Reduction of Animals in Research

[/fusion_tab][fusion_tab title=”Features and Benefits” icon=””]

Features that help you do better science…

Scientists can collect longitudinal data for longer duration and reuse implants in new subjects

Digital data transmission with inductive charging and battery backup to enable 24/7 digital data collection

Unique implant IDs permit multiple animals per cage, improving surgical recovery and optimizing throughput

Up to 3m recording range allows you to remove animals from the pads for short-term testing

 

 

 

 

 

 

 

 

 

Wireless Data Recording and Charging

Advanced wireless technology allows one pad station to collect data from multiple subjects simultaneously. Included wireless implant chargers allow implants to record in subjects for extended periods. Analog outputs from the pads connect directly to any compatible data acquisition system (DAQ) using standard BNC connections.

 

 

[/fusion_table]

Wireless Implants

These small biocompatible devices are surgically implanted subcutaneously or within the subject’s peritoneal cavity, with ECG leads sutured to the pectoral muscles, one on each side of the chest. Once implanted, the devices can be wirelessly set to automatically collect ECG, heart rate, core temperature, and activity data at defined time periods and intervals.

 

 

[/fusion_table]

Mouse Temperature/Activity Implants

 

 

Wireless Data Recording and Charging

 

 

Wireless Implants

These small biocompatible devices are surgically implanted subcutaneously or within the subject’s peritoneal cavity, with ECG leads sutured to the pectoral muscles, one on each side of the chest. Once implanted, the devices can be wirelessly set to automatically collect ECG, heart rate, core temperature, and activity data at defined time periods and intervals.