(June 8, 2021) Doppler Flow Velocity Assessment as an Index of Cardiovascular Health in Preclinical Studies

During this webinar Dr. Anand Narayanan reviewed the cardiovascular physiology principles and how cardiovascular systems adapt in the context of old age and exercise.

Dr. Narayanan’s research focuses on the effects of old age and exercise training on cardiovascular physiology.

Learning Objectives:

  • How old age and exercise training affect cardiovascular, and associated organ, physiology
  • Doppler measurement results from old age and exercise training study
  • Overview of Doppler Flow Velocity and its implementation


The cardiovascular system includes the heart, arteries, veins, and lymphatics. The heart, arteries, and veins transport and serve blood to and from all organs of the body, with blood containing macro- and micronutrients, oxygen, water, and carbon dioxide, while the lymphatic system transports lymph, which contains excess fluid and macromolecules not collected by the veins. Adequate blood perfusion is required to maintain organ system physiology and metabolism, and decrements in regional blood may lead to pathology. Old age, as one example, comes with various adaptations including decreased blood perfusion coupled with bone loss, e.g. osteoporosis. Exercise training has been shown to side-effects from old age by improving blood perfusion to organs such as bones, in turn improving bone health and lowering the risk of osteoporosis development.

About the Speaker (s)

Dr. Anand Narayanan  

NASA Space Biology Postdoctoral Fellow, Florida State University 

Dr. Anand Narayanan has an interdisciplinary background in engineering, biology, and physiology, with specialized training in cardiovascular sciences, in lymphatics while at Texas A&M University and in heart and blood vascular adaptations now at Florida State University, having also studied cardiovascular-coupled organ system adaptations including cerebral, musculoskeletal, and gastrointestinal physiology. He has more than 10 years of physiology and immunology experience, in various research areas including auto-immune conditions, old age, exercise training, etc. His current research focuses on the interaction between the immune system and how it affects cardiovascular physiology.